- Artist: Leonardo da Vinci
- Year: 1494–1498
- Medium: tempera on gesso, pitch and mastic
- Dimensions: 460 cm × 880 cm (181 in × 346 in)
- Location: Santa Maria delle Grazie, Milan
The Last Supper (Italian: Il Cenacolo or L'Ultima Cena) is a late 15th-century mural painting by Leonardo da Vinci in the refectory of the Convent of Santa Maria delle Grazie, Milan. It is one of the world's most famous paintings, and one of the most studied, scrutinized, and satirized. The work is presumed to have been commenced around 1495 and was commissioned as part of a scheme of renovations to the church and its convent buildings by Leonardo's patron Ludovico Sforza, Duke of Milan. The painting represents the scene of The Last Supper of Jesus with his disciples, as it is told in the Gospel of John, 13:21. Leonardo has depicted the consternation that occurred among the Twelve Disciples when Jesus announced that one of them would betray him. Due to the methods used, and a variety of environmental factors, very little of the original painting remains today, despite numerous restoration attempts, the last being completed in 1999.